| LEADER 00000cam 2200469 a 4500 |
| 008 121002s20119999th 000 0 eng d |
| 020 ^a9780123822130 |
| 099 ^aPY9^bRe344R |
| 245 00 ^aRegulation of organelle and cell compartment signaling /^ceditors-in-chief, Ralph A. Bradshaw, Edward A. Dennis. |
| 250 ^a1st ed. |
| 260 Amsterdam ;^aBoston :^bElsevier/Academic Press,^c2011. |
| 300 ^axvii, 533 p. :^bill. (some col.) ;^c28 cm |
| 504 ^aIncludes bibliographical references and index. |
| 520 ^a^"Cell signaling, which is also often referred to as signaltransduction or, in more specialized cases, transmembranesignaling, is the process by which cells communicate withtheir environment and respond temporally to external cuesthat they sense there. All cells have the capacity toachieve this to some degree, albeit with a wide variationin purpose, mechanism, and response. At the same time,there is a remarkable degree of similarity over quite arange of species, particularly in the eukaryotic kingdom,and comparative physiology has been a useful tool in thedevelopment of this field. The central importance of thisgeneral phenomenon (sensing of external stimuli by cells)has been appreciated for a long time, but it has trulybecome a dominant part of cell and molecular biologyresearch in the past three decades, in part because adescription of the dynamic responses of cells to externalstimuli is, in essence, a description of the life processitself. This approach lies at the core of the developingfields of proteomics and metabolomics, and its importanceto human and animal health is already plainly evident^"--Provided by publisher. |
| 650 0 ^aCellular signal transduction. |
| 650 0 ^aCell organelles. |
| 650 0 ^aTranscription factors. |
| 650 12 ^aSignal Transduction. |
| 650 22 ^aCell Cycle Proteins. |
| 650 22 ^aGene Expression Regulation. |
| 650 22 ^aOrganelles. |
| 650 22 ^aTranscription Factors. |
| 700 1 ^aBradshaw, Ralph A.,^d1941- |
| 700 1 ^aDennis, Edward A. |
| 999 ^aอรทัย โคตรธาดา |
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