LEADER 00000cam 2200457 i 4500 |
008 121122s20119999th 000 0 eng d |
020 ^a9780813829937 (hardback : alk. paper) |
020 ^a0813829933 (hardback : alk. paper) |
099 ^aPH8^bRi625C |
100 1 ^aRiviere, Jim E.^q(Jim Edmond),^eauthor |
245 10 ^aComparative pharmacokinetics :^bprinciples, techniques,and applications /^cJim E. Riviere |
250 ^a2 Edition |
260 ^aChichester, West Sussex, UK :^bWiley-Blackwell,^c2011,©2011 |
300 ^ax, 443 pages :^billustrations ;^c26 cm |
504 ^aIncludes bibliographical references and index |
505 0 ^aChapter 1: Introduction -- Chapter 2: Principles of drugmovement in the body -- Chapter 3: Quantitative structure-permeability relationships / with Xin-Rui Xia -- Chapter 4: Absorption -- Chapter 5: Distribution / with JenniferBuur -- Chapter 6: Renal elimination -- Chapter 7: Hepaticbiotransformation and biliary excretion / with RonaldBaynes -- Chapter 8: Compartmental models -- Chapter 9:Noncompartmental models -- Chapter 10: Nonlinear models --Chapter 11: Physiological models / with Teresa Leavens --Chapter 12: Dosage regimens -- Chapter 13: Simultaneouspharmacokinetic-pharmacodynamic modeling / with Pierre-Louis Toutain -- Chapter 14: Study design and dataanalysis / with Jason Chittenden - Chapter 15:Bioequivalence Studies / with Marilyn Martinez -- Chapter16: Population pharmacokinetic models / with JasonChittenden -- Chapter 17: Dosage adjustments in diseasestates / with Jennifer Davis -- Chapter 18: Interspeciesextrapolations -- Chapter 19: Tissue residues andwithdrawal times / with Sharon Mason |
520 ^a^"Now in a newly revised edition, ComparativePharmacokinetics presents the principles and techniques ofpharmacokinetics in a detailed, yet practical and easilyunderstandable manner. Coverage includes an overview ofthe basic physiologic processes of drug absorption anddisposition and detailed explanation of pharmacokineticmeans of measuring and predicting these processes by wayof mechanistic and empirical models, as well as extensivecoverage of dosage regimens and adjustments, interspeciesextrapolation, experimental design, data collection andanalysis, and residues and withdrawal times^"--Provided bypublisher |
650 0 ^aPharmacokinetics |
650 0 ^aVeterinary pharmacology |
650 12 ^aPharmacokinetics |
999 ^aอรทัย โคตรธาดา |